Ageing

S3E8: Muscle Loss, Sarcopenia, and Implications for Healthy Ageing w/ Dr. Theo Ispoglou PhD

Season 3, Epsiode 8

Dr. Bubbs interviews Dr. Theocharis Ispoglou PhD to discuss the importance of muscle mass in healthy ageing and how age-related sarcopenia can compromise healthspan and longevity. In this episode, Dr. Ispoglou defines sarcopenia, discusses the most common causes and how this can impact your life expectancy. He also talks about key factors that can accelerate muscle loss, common tests that can be performed to assess for age-associated muscle loss and the impacts of novel forms of protein to preserve lean muscle and much, much more!

Summary of Episode

2:45 – Definition of sarcopenia

4:30 – Causes of sarcopenia

7:10 – Losses of lean muscle after 50

9:30 – Leucine supplementation and older adults

15:00 – How leucine demand increases as we age

19:45 – Effect of protein gel vs. protein on appetite in older adults

23:00 – Should we raise the RDA of protein in older adults?

27:30 – Old myths - dangers of egg consumption and effects of protein on kidneys

30:00 – Common tests for age-related muscle loss

36:45 – Solutions for prevention of age-related sarcopenia

Links to Research Papers

Novel essential amino acid supplements enriched with L-leucine facilitate increased protein and energy intakes in older women: a randomised controlled trial

Double-blind, placebo-controlled pilot trial of L-Leucine-enriched amino-acid mixtures on body composition and physical performance in men and women aged 65–75 years

Daily L-leucine supplementation in novice trainees during a 12-week weight training program.

About Dr. Theocharis Ispoglou PhD

Dr. Theocharis Ispoglou PhD is a Reader in Nutrition and Muscle Health at Leeds Beckett University. He has a keen interest and expertise in studying the effects of nutritional and exercise interventions as a means to optimise human performance. In particular, identifying evidence-based strategies to prevent, minimize or treat sarcopenia. Contact Dr. Ispoglou via the Leeds Beckett website or follow on Twitter @Theo_Ispoglou.

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S3E6: Longevity, 7 Pathways of Ageing & Increasing Healthspan w/ Dr. Rocco Monto MD

Season 3, Episode 6

Dr. Bubbs interviews Dr. Rocco Monto MD, award-winning orthopedic surgeon, team physician for US Soccer, and author of 'The Fountain: A Doctor's Prescription to Make 60 the New 30'. In this episode, Dr. Monto talks about the Blue Zones and the common themes in their longevity, outlines the 7 pathways of ageing, and highlights howmitochondrial  dysfunction plays a key role in ageing.

Summary of This Episode

5:30 – Blue zones and longevity

7:45 – 7 pathways of ageing

9:40 – Mitochondrial dysfunction and ageing

13:20 – Chronic inflammation and longevity

16:00 – Time-restricted feeding strategies

24:30 – Supplemental testosterone, medications and longevity

27:15 – Nicotinamide riboside (NR) supplements and ageing

29:30 – Exercise and longevity

34:30 – Social connectivity, meditation and the importance of mentors

43:00 – Dr. Monto’s simple tip for increasing healthspan

Link to Rocco’s Book

The Fountain

About Dr. Rocco Monto MD

Dr. Rocco Monto MD is an an award-winning orthopedic surgeon and sports medicine specialist, internationally recognized for his pioneering clinical research on regenerative medicine and innovative approach to complex medical issues. Dr. Monto is also a team physician for US Soccer, a medical consultant for a global portfolio of elite athletes, and author of the new book, The Fountain: A Doctor's Prescription to Make to Make 60 the New 30Learn more at drmonto.com.

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