Insulin

S4E18: Why We Get Sick: Hyper-Insulinemia & Chronic Disease w/ Dr. Ben Bikman, PhD

Season 4, Episode 18

Dr. Marc Bubbs interviews scientist and insulin expert Dr. Ben Bikman, PhD to discuss how chronically high insulin levels can drive chronic disease states.

Summary of Episode

3:05 – Why did we get sick 100 years ago compared to today?

5:45 – Why insulin resistance is at the root of most chronic conditions

7:45 – Hyper-insulinemia and weight gain

10:40 – The insulin resistance and heart disease connection (and why it matters)

14:20 – How chronically high blood glucose levels impair your vascular health

16:50 – Football lineman, metabolic profiles and the role of fitness and exercise

23:40 – Taking insulin and how it impacts your fat cells (in diabetics)

28:20 – Why insulin as a medication for type-2 diabetes is a short-sighted approach

32:05 – The connection between insulin resistance and brain function

38:04 – Is there an application for exogenous ketones to prevent (or delay) dementia

39:05 – Dietary strategies to support insulin resistance

46:45 – Blood tests for assessing the degree of insulin resistance

49:05 – Exercise and insulin sensitivity: resistance and aerobic activity

 

About Dr. Ben Bikman, PhD  

Ben Bikman, Ph.D. is a professor of pathophysiology and biomedical scientist whose research agenda focuses on the molecular mediators of obesity and its co-morbidities. Employing cell-autonomous to whole-body systems, his lab’s main efforts explore the intimate associations between the metabolic and immune systems. Most recently his most recent work has focused on scrutinizing the role of ketones as metabolic signaling molecules. 

@BenBikmanPhD

The Bikman Lab

GetHlth.com

  

Research Papers & Book

Why We Get Sick

Improvement in Glycemic and Lipid Profiles in Type 2 Diabetics with a 90-Day Ketogenic Diet

Insulin selectively reduces mitochondrial uncoupling in brown adipose tissue in mice


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